|
KMID : 0613820090190020234
|
|
Journal of Life Science
2009 Volume.19 No. 2 p.234 ~ p.240
|
|
|
Prevalence of HPV Infection and HPV Genotype Spectrum among Sexually High-Risk Women in Busan
|
|
Min Sang-Kee
Kim Seong-Sun
Choi Byeong-Sun
Cho Kyung-Soon
Lee Joo-Yeon
Kim Seong-Joon
Bin Jae-Hun
Park Ho-Kuk
|
|
|
Abstract
|
|
|
|
We tried to analyze the HPV prevalence and HPV genotypes of sexually high-risk women living in Busan, the biggest seaport of South Korea. Six hundred sixty women engaging in high-risk occupations participated in this study. The prevalence of HPV infection and HPV genotyping were determined with HPVDNA chip, which consisted of 16 high-risk HPV genotypes (oncogenic genotypes) and 8 low-risk HPV genotypes. The overall prevalence of HPV infection in this study population was 39.1% (258/660) and the 20’s showed the highest prevalence of HPV infection (51.5%). The dominant HPV genotypes including single or multiple HPV-infected women were resulted in HPV-16 (15.9%), -53 (10.2%), -58 (7.7%), -18 (5.2%) in case of high-risk HPV genotype and HPV-70 (10.4%), -6 (4.1%), -11 (2.0%) in case of low-risk HPV genotypes. Remarkably, the proportion of women infected with high-risk HPV genotypes (62.0%) was almost four times higher than those of women infected with low-risk HPV genotypes (14.7%) and high/low-risk HPV genotypes (12.0%). Among the 258 HPV-infected women, single infection was 175, double infection 66, triple infection 12, quadruple infection 4, quintuple infection 1, respectively. Our finding suggests that the introduction and development of effective HPV vaccines should consider the current status of HPV genotypic infection in South Korean women.
|
|
|
KEYWORD
|
|
|
HPV genotype, HPVDNA chip, sexually high-risk women
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|